Evaluating kidney and heart benefits of SGLT2 inhibitors for patients with diabetes and kidney disease

Evaluating kidney and heart benefits of SGLT2 inhibitors for patients with diabetes and kidney disease dr freeman type 2 diabetes cure In a nutshell This review looked at SGLT2 inhibitor medications for people with both type 2 diabetes (T2D) and Read more

Savvy Updates, 10/11/21: Omnipod 5 Impressive, (2) Medtronic Pump Recalls, Mannkind’s Afrezza Trial for Peds, Non-Invasive CGMs: GraphWear & KnowU, Medicare Drug Pricing under Review, Kidney Disease Research

Savvy Updates, 10/11/21: Omnipod 5 Impressive, (2) Medtronic Pump Recalls, Mannkind’s Afrezza Trial for Peds, Non-Invasive CGMs: GraphWear & KnowU, Medicare Drug Pricing under Review, Kidney Disease Research type 2 diabetes can be reversed FDA Approval of Omnipod 5 Looks Read more

Savvy Updates, 9/19/21: Kaleido Mini Patch Pump, Eversense for Medicare patients, Chronic Kidney Disease Meds, Medicare’s $35 Insulin Copay, Gut and Meds, Sparkling Waters

Savvy Updates, 9/19/21: Kaleido Mini Patch Pump, Eversense for Medicare patients, Chronic Kidney Disease Meds, Medicare’s Insulin Copay, Gut and Meds, Sparkling Waters type 2 diabetes can be reversed This mini insulin pump makes people with diabetes just a little Read more

Is closed-loop glucose control an effective treatment for patients with type 2 diabetes with serious kidney disease?

Is closed-loop glucose control an effective treatment for patients with type 2 diabetes with serious kidney disease? dr freeman type 2 diabetes cure In a nutshell This study looked at the use of closed-loop glucose control treatment for patients with Read more

‘A simple proposal : Reduce sugar, reduce disease.’

‘A simple proposal : Reduce sugar, reduce disease.’ diet for type 2 diabetes reversal https://1.bp.blogspot.com/-M_YZ5OxJm6k/YSq069ypjdI/AAAAAAAAa8c/YR_9HXTXUGYNTQt7Whm3PgzoFcMQXUi3gCLcBGAsYHQ/s72-w640-h427-c/sugarfromspoon.jpg From The Harvard Gazette: “Reducing sugar in packaged foods can prevent disease in millions A new health and economic model clearly shows why it’s imperative Read more

Do eye injections reduce the risk of blindness in patients with severe diabetic eye disease?

Do eye injections reduce the risk of blindness in patients with severe diabetic eye disease? dr freeman type 2 diabetes cure In a nutshell This study looked at the use of aflibercept (Eylea) eye injections for the treatment of severe nonproliferative diabetic Read more

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (Gip) Levels and Cardiovascular Disease Risk are Driven by Distinct Causal Variants in the Gipr Region

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (Gip) Levels and Cardiovascular Disease Risk are Driven by Distinct Causal Variants in the Gipr Region james freeman diabetes freedom There is considerable interest in GIPR agonism to enhance the insulinotropic and extra-pancreatic effects of Read more

Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease

Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease james freeman diabetes freedom Effective treatment of diabetic kidney disease (DKD) remains a large unmet medical need. Within the disease’s complicated pathogenic mechanism, activation of Read more

Savvy Updates 8/23/21: Beta Cells START Immune Attack, Immune System Proteins, GastroP & Closed Loops, Kidney Disease Proteins, ‘Apricot’ Undersea Cable Project

Savvy Updates 8/23/21: Beta Cells START Immune Attack, Immune System Proteins, GastroP & Closed Loops, Kidney Disease Proteins, ‘Apricot’ Undersea Cable Project type 2 diabetes can be reversed In Autoimmune Disease, Organs May Lure the Immune System into an Attack Read more

Savvy Updates, 8/16/21: GWave Non-Invasive CGM, Pancreatic Beta Cell Boost, Kidney Disease “Treasury Map”

Savvy Updates, 8/16/21: GWave Non-Invasive CGM, Pancreatic Beta Cell Boost, Kidney Disease “Treasury Map” type 2 diabetes can be reversed Diabetes startup brews up $ 11M after ‘serendipitous spill’ led to creation of new CGM tech was reported by Andrea Read more

A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease

A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease james freeman diabetes freedom Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes (T2D). We aimed to Read more

Vaccination against receptor for advanced glycation end products attenuates the progression of diabetic kidney disease

Vaccination against receptor for advanced glycation end products attenuates the progression of diabetic kidney disease james freeman diabetes freedom Effective treatment of diabetic kidney disease (DKD) remains a large unmet medical need. Within the disease’s complicated pathogenic mechanism, activation of Read more

Perirenal fat thickness is significantly associated with the risk for development of chronic kidney disease in diabetic patients

Perirenal fat thickness is significantly associated with the risk for development of chronic kidney disease in diabetic patients james freeman diabetes freedom Perirenal fat is adjacent to kidneys and active in metabolism and adipokine secretion. We aimed to investigate whether Read more

Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease

Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease james freeman diabetes freedom To understand the causal role of adiposity and ectopic fat in type 2 diabetes and cardiometabolic diseases, we Read more

Finerenone: New Drug to Prevent Chronic Kidney Disease and Cardiovascular Death in Type 2 Diabetes

Finerenone: New Drug to Prevent Chronic Kidney Disease and Cardiovascular Death in Type 2 Diabetes if you have type 2 diabetes can it be reversed Verbatim from the FDA press release: FDA has approved Kerendia (finerenone) tablets to reduce the Read more

Effect of pioglitazone treatment in patients with prediabetes or type 2 diabetes mellitus and liver disease.

Effect of pioglitazone treatment in patients with prediabetes or type 2 diabetes mellitus and liver disease. dr freeman type 2 diabetes cure In a nutshell This study analyzed the effectiveness of pioglitazone (Actos) in patients with prediabetes or type 2 diabetes (T2D) Read more

Ketogenic Diet Improved Non-Alcoholic Fatty Liver Disease In Just Six Days

Ketogenic Diet Improved Non-Alcoholic Fatty Liver Disease In Just Six Days if you have type 2 diabetes can it be reversed https://paleodiabetic.files.wordpress.com/2013/12/img_1394.jpg There’s a silent epidemic in folks with type 2 diabetes: 50 to 70% have non-alcoholic fatty liver disease. Non-alcoholic Read more

The low-expression variant of FABP4 is associated with cardiovascular disease in type 1 diabetes

The low-expression variant of FABP4 is associated with cardiovascular disease in type 1 diabetes james freeman diabetes freedom Fatty-acid binding protein 4 (FABP4) is implicated in the pathogenesis of cardiometabolic disorders. Pharmacological inhibition or genetic deletion of FABP4 improves cardiometabolic Read more

Can melatonin help relieve pain in patients with painful diabetic nerve disease?

Can melatonin help relieve pain in patients with painful diabetic nerve disease? dr freeman type 2 diabetes cure In a nutshell This study aimed to explore the effects of melatonin in addition to pregabalin (Lyrica) for the management of painful diabetic neuropathy (PDN). Read more

Mutations of NRG4 contribute to the pathogenesis of non-alcoholic fatty liver disease and related metabolic disorders

Mutations of NRG4 contribute to the pathogenesis of non-alcoholic fatty liver disease and related metabolic disorders james freeman diabetes freedom Neuregulin 4 (Nrg4), an adipose tissue–enriched endocrine factor, participates in adipocyte-to-hepatocyte communication, eliciting beneficial metabolic effects in non-alcoholic fatty liver Read more

Savvy Updates, 6/28/21: 100th Anniversary of the Discovery of Insulin, Inhaled Insulin Study, Happiness, T1D and Kidney disease, CHOCOLATE!?,

Savvy Updates, 6/28/21: 100th Anniversary of the Discovery of Insulin, Inhaled Insulin Study, Happiness, T1D and Kidney disease, CHOCOLATE!?, type 2 diabetes can be reversed Top Highlights from the ADA Scientific Sessions 2021   Inhaled insulin shows positive results in people Read more