Distinct Characteristics between Perivascular and Subcutaneous Adipose Derived Stem Cells

Distinct Characteristics between Perivascular and Subcutaneous Adipose Derived Stem Cells james freeman diabetes freedom Adipose derived stem cells (ADSCs) can differentiate into vascular lineages and participate in vascular remodeling. Perivascular ADSCs (PV-ADSCs) draw attention due to their unique location. The Read more

JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance

JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance james freeman diabetes freedom Chronic low-grade inflammation, often referred to as metainflammation, develops in response to overnutrition and is a major player in the regulation of insulin sensitivity. Read more

Closing the Loop: Algorithm Based Communication Between Your Insulin Pump and Continuous Glucose Monitor

Closing the Loop: Algorithm Based Communication Between Your Insulin Pump and Continuous Glucose Monitor diabetes reversing foods We are currently in the midst of a technological revolution in Type 1 diabetes management, commonly referred to as “hybrid closed-loop systems (HCL).” Read more

Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index

Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index james freeman diabetes freedom We assessed whether the relationship between insulin secretion and sensitivity predicted development of type 2 Read more

Leukocyte Counts and T Cell Frequencies Differ Between Novel Subgroups of Diabetes and Associate with Metabolic Parameters and Biomarkers of Inflammation

Leukocyte Counts and T Cell Frequencies Differ Between Novel Subgroups of Diabetes and Associate with Metabolic Parameters and Biomarkers of Inflammation james freeman diabetes freedom Frequencies of circulating immune cells are altered in type 1 and type 2 diabetes compared Read more

The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank

The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank james freeman diabetes freedom We investigated the relationship between glycaemia and cognitive function, brain structure and incident dementia using bidirectional Mendelian Read more